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Or explore alternative tirzepatide delivery methods that may reduce GI side effects

This gene produces an enzyme in the liver responsible for breaking down caffeine, and certain gene variants metabolize caffeine at different rates (Sadeghi et al., 2019)

Randomized controlled trials show oral semaglutide produces 7-15% body weight reduction over 68 weeks, with consistent improvements in blood sugar control and cardiovascular markers

Other potential confounding factors, such as differences in SOC, patient selection criteria, and GC use patterns, cannot be ruled out

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